[关键词]
[摘要]
丸、散剂作为传统中药的主流剂型,具有鲜明的剂型特色,对疾病的选择、方药的加工以及在体内的释放都有其自身的规律与特点,但因制剂工艺粗糙、服用量大、质量难以控制、品相差等缺点导致患者顺应性降低,制约了其发展。结合传统丸、散剂的特点,通过实践提出了一种中药制剂新技术——中药粒子设计技术。着重对中药粒子设计技术的基本概念及特点、基本原理、实施方式、用途等方面进行了详细论述,为传统丸、散剂的品质提升与产业升级提供新的研究思路。
[Key word]
[Abstract]
Pill and powder with obvious characteristics are the main dosage forms of traditional Chinese materia medica. The two dosage forms have principles and characteristics in selection of diseases, processing, and in vivo release of prescriptions. But the development was limited because of the decrease of compliance of patients due to shortages like crude preparation process and large dosage. To combine with the characteristics of traditional pill and powder, authors suggest a new technology in pharmaceutics through practice, that is particles design technology for Chinese materia medica. In this article, the basic concept and features, basic principles, implementation methods, intended use of the ten aspects on particles design technology for Chinese materia medica are discussed in detail. Authors believe that the new research ideas on the quality improvement and industrial upgrading for the traditional pill and powder will be put forward in this new technology.
[中图分类号]
[基金项目]