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[摘要]
目的 研究尾叶香茶菜Rabdosia excisa的化学成分。方法 利用硅胶柱色谱法进行分离和纯化,通过理化性质和波谱数据鉴定化合物结构。结果 从尾叶香茶菜中分离鉴定了15个化合物,分别为山香三萜二烯酸(1)、α-香树脂醇棕榈酸酯(2)、豆甾醇(3)、β-谷甾醇(4)、棕榈酸(5)、熊果酸(6)、1α, 6, 11β, 15β-四乙酰基-6, 7-断裂-7, 20-内酯-对映-贝壳杉-16-烯(7)、2α, 3α-二羟基乌苏-12-烯-28-酸(8)、马斯里酸(9)、2α, 3α, 19-三羟基-12-烯-28-乌索酸(10)、毛叶香茶菜素E(11)、6β, 11α, 15α-三羟基-6, 7断裂-6, 20-环氧2-1α, 7-内酯-对映-贝壳杉-16-烯(12)、对映-7α, 20-环氧-贝壳杉烷-16-烯-1α, 6β, 7β, 14β, 15β-五醇-1-O-葡萄吡喃糖苷(13)、冬凌草甲素(14)、胡萝卜苷(15)。结论 除了化合物3、5、6、14、15外,其余化合物均为首次从尾叶香茶菜中发现。
[Key word]
[Abstract]
Objective To research the chemical constituents of Rabdosia excisa. Methods Compounds were separated and purified by silica gel column chromatography and their structures were determined by spectroscopic method. Results Fifteen compounds isolated from the leaves of this plant were identified as: hyptadienic acid (1), α-amyrin palmitate (2), stigmasterol (3), β-sitosterol (4), palmitic acid (5), ursolic acid (6), 1α, 6, 11β, 15β-tetraacetoy-6, 7-seco-7, 20-olide-ent-kaur-16-en (7), 2α, 3α-dihydroxy-urs- 12-en-28-oic acid (8), maslinic acid (9), 2α, 3α, 19-trihydroxy-urs-12-en-28-oic acid (10), maoyecrystal E (11); 6β, 11α, 15α- trihydroxy-6, 7-seco-6, 20-epoxy-1α, 7-olide-ent-kaur-6-en, epinodosinol (12), enmenol-glucoside (13), oridonol (14), and daucosterol (15). Conclusion All the constituents are found in R. excisa for the first time except constituents 3, 5, 6, 14, and 15.
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[基金项目]
河南省基础与前沿技术研究计划项目(102300410006)