[关键词]
[摘要]
目的 研究通关藤Marsdenia tenacissima茎的化学成分。方法 采用正反相硅胶柱色谱法进行分离纯化,结合MS、IR、NMR波谱数据及理化性质鉴定化合物的结构。结果 从通关藤茎中分离得到两个孕甾醇苷类化合物,分别鉴定为:11α-丁烯酰基-通关藤苷元B-3-O-β-葡萄糖吡喃基-(1→4)-3-O-甲基-6-脱氧-β-阿洛糖吡喃基-(1→4)-β-齐墩果糖吡喃糖苷,命名为通关藤苷I(1);11α, 12β-二-乙酰-通关藤苷元B-3-O-β-葡萄糖吡喃基-(1→4)-3-O-甲基-6-脱氧-β-阿洛糖吡喃基-(1→4)-β-齐墩果糖吡喃糖苷(通关藤苷K,2)。结论 化合物1为新化合物,化合物2为首次从通关藤中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the stems of Marsdenia tenacissima. Methods The chemical constituents were isolated and purified by various column chromatographic methods. Their structures were identified on the basis of spectral data and chemical analysis. Results Two pregnane glycosides were isolated from the stems of M. tenacissima and identified as 3-O-β-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-allopyranosyl-(1→4)-β-oleandropyranosyl-11α-O-tigloyltenacigenin B, named as tenacigenoside I (1); 3-O-β-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-allopyranosyl-(1→4)-β-oleandropyranosyl-11α, 12β- di-O-acetyltenacigenin B (tenacigenoside K, 2). Conclusion Compound 1 is a new compound and compound 2 is obtained from the M. tenacissima for the first time.
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[基金项目]
西南民族大学博士启动基金资助项目(26701001)