[关键词]
[摘要]
目的:对龙须菜Gracilaria lemaneiformis的化学成分进行研究。方法 采用正相硅胶柱色谱、Sephadex LH-20凝胶柱色谱等方法进行分离纯化,运用波谱分析的方法鉴定化合物的结构。结果 分离并鉴定了9个化合物:棕榈酸(1)、1, 3-双棕榈酸甘油酯(2)、1-棕榈酸单甘油酯(3)、尿嘧啶(4)、腺嘌呤核苷(5)、2α-氧杂-2-氧-5α-羟基-3, 4-二失碳胆甾烷(6)、1-O-β-D-半乳糖-(6→1)-α-D-半乳糖-2, 3-O-十六烷酸甘油二酯(7)、1-O-α-D-吡喃葡萄糖-2, 3-O-十六烷酸甘油二酯(8)、β-谷甾醇(9)。结论 以上化合物均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents of Gracilaria lemaneiformis. Methods Compounds were isolated by normal phase silica gel and Sephadex LH-20 gel column chromatography. Their structures were elucidated by analyses of spectroscopic data. Results Nine compounds were isolated from the ethanol extract of G. lemaneiformis, their structures were elucidated as palmitic acid (1), 1, 3-dipalmitin (2), 1-monopalmitin (3), uracil (4), adenosine (5), 2α-oxa-2-oxo-5α-hydroxy-3,4- dinorcholestane (6), 1-O-β-D-galactosyl-(6→1)-α-D-galactosyl-2, 3-O-dihexadecanoyl-glycerol (7), 1-O-α-D-glucose-2,3-O- dihexadecanoyl-glycerol (8), and β-sitosterol (9). Conclusion All of these compounds are obtained from this plant for the first time.
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[基金项目]
国家中医药管理局课题(06-07ZQ14);四川省教育厅重点项目(07ZA017)