[关键词]
[摘要]
目的 研究金锦香 Osbeckia chinensis 的化学成分。方法 利用硅胶柱色谱与Sephadex LH-20凝胶柱色谱进行分离和纯化,根据化合物的理化数据和波谱数据鉴定其结构。结果 从金锦香全草乙醇提取物中分离鉴定了16个化合物:3-甲氧基-鞣花酸-4-O-β-D-吡喃葡萄糖苷(1)、3, 3′-二甲氧基-鞣花酸-4-O-β-D-吡喃葡萄糖苷(2)、3, 3′, 4′-三甲氧基-鞣花酸-4-O- β-D-吡喃葡萄糖苷(3)、山柰酚-3-O-β-L-吡喃鼠李糖苷(4)、槲皮素-3-O-β-D-吡喃半乳糖苷(5)、槲皮素-3-O-β-L-吡喃鼠李糖苷(6)、山柰酚-6-C-β-D-吡喃葡萄糖苷(7)、槲皮素-3-O-β-L-吡喃鼠李糖苷-2″-乙酸酯(8)、山柰酚-3-O-β-D-吡喃葡萄糖苷-3″, 6″-二-E-(4-羟基)-肉桂酸酯(9)、4′-hydroxyflavone-3-O-(6-O-trans-p-coumaroyl)-β-D-glucopyranoside(10)、山柰酚-3-O- β-D-吡喃葡萄糖苷-6″-E-(4-羟基)-肉桂酸酯(11)、3β-hydroxy-9(11)-fernen-23-oic acid(12)、1, 2-dihydroxy-9(11)-arborinen-3-one(13)、cholest-5-ene-2, 3, 21-triol(14)、β-谷甾醇(15)、胡萝卜苷(16)。结论 除化合物5和16外,其余化合物均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents from Osbeckia chinensis. Methods The constituents were separated by column chromatography and their structures were elucidated by spectral data analyses. Results Sixteen compounds were isolated from O. chinensis and identified as 4-O-β-D-glucopyranosyl-3-O-methylellagic acid (1), 4-O-β-D-glucopyranosyl-3,3′-di-O- methylellagic acid (2), 4-O-β-D-glucopyranosyl-3,3′,4′-tri-O-methylellagic acid (3), kaempferol-3-O-β-L-ramnopyranoside (4), quercetin-3-O-β-D-galactopyranoside (5), quercetin-3-O-β-L-rhamnopyranoside (6), kaempferol-6-C-β-D-glucopyranoside (7), quercetin-3-O-β-L-rhamnopyranosyl-2″-acetyl (8), kaempferol-3-O-β-D-glucopyranosyl-2″,6″-bis-O-E-(4-hydroxy)-cinnamoyl (9) 4′-hydroxyflavone-3-O-(6-O-trans-p-coumaroyl)-β-D-glucopyranoside (10), kaempferol-3-O-β-D-glucopyranosyl-6″-O-E-(4-hydroxy)- cinnamoyl (11), 3β-hydroxy-9(11)-fernen-23-oic acid (12), 1,2-dihydroxy-9(11)-arborinen-3-one (13), cholest-5-ene-2,3,21-triol (14), β-sitosterol (15), and daucosterol (16). Conclusion Except for compounds 5 and 16, all compounds are obtained from O. chinensis for the first time.
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[基金项目]
云南省科技计划面上项目(2008CD159)