[关键词]
[摘要]
目的 研究无叶假木贼Anabasis aphylla的化学成分。方法 采用硅胶、薄层制备、葡聚糖凝胶以及制备型HPLC色谱进行分离纯化,利用MS、IR和NMR等波谱学方法鉴定化合物的结构。结果 分离得到15个化合物,分别鉴定为顺式咖啡酰二十烷醇酯(1)、反式咖啡酰二十烷醇酯(2)、反式咖啡酰十三烷醇酯(3)、反式咖啡酰十六烷醇酯(4)、反式咖啡酰十八烷醇酯(5)、反式咖啡酰二十二烷醇酯(6)、反式咖啡酰二十四烷醇酯(7)、反式阿魏酰二十烷醇酯(8)、反式阿魏酰二十二烷醇酯(9)、反式阿魏酰二十四烷醇酯(10)、4-羟基苯乙酮(11)、正十三碳酸(12)、正十四碳酸(13)、胡萝卜苷(14)、β-谷甾醇(15)。结论 化合物1为新化合物,2~13为首次从假木贼属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from the aerial parts of Anabasis aphylla. Methods The chemical constituents were isolated and purified by silica gel column, Sephadex LH-20, prep-TLC, and prep-HPLC. Spectroscopic methods, such as MS, IR, and NMR spectra were used for the structural identification. Results Fifteen compounds were isolated and identified as: eicosyl-(Z)-caffeate (1), eicosyl-(E)-caffeate (2), trydecyl-(E)-caffeate (3), hexadecyl-(E)-caffeate (4), octadecyl-(E)-caffeate (5), docosyl-(E)-caffeate (6), tetracosyl-(E)-caffeate (7), eicosyl-(E)-ferulate (8), docosyl-(E)-ferulate (9), tetracosyl-(E)-ferulate (10), 4-hydroxyacetophen-one (11), n-tridecanoic acid (12), n-myristic acid (13), daucosterol (14), and β-sitosterol (15). Conclusion Compound 1 is a new compound, and compounds 2―13 are isolated from the plants in Anabasis L. for the first time.
[中图分类号]
[基金项目]
国家科技重大专项(2009zx09504-004)