[关键词]
[摘要]
目的研究黄花獐牙菜Swertia kingii的化学成分。方法用各种色谱柱方法进行分离纯化, 根据理化性质和波谱解析鉴定其化学结构。结果从黄花獐牙菜中分离到15个化合物, 鉴定了其中的11个化合物, 分别为β-谷甾醇(-βsitosterol, 1)、1, 8-二羟基-3, 7-二甲氧基酮(甲基獐牙菜宁, methylswertianin, 2)、1, 7-二羟基-3, 8-二甲氧基酮(gentiacaulein, 3)、1, 8-二羟基-3, 5-二甲氧基酮(印度獐牙菜素, swerchirin, 4)、8-O-β-D-吡喃葡萄糖-1, 3, 7-三羟基酮(8-O-β--Dglucopyranosyl-1, 3, 7-trihydroxanthone, 5)、芒果苷(mangiferin, 7)、1-O-[β-D-吡喃木糖(1→6)-β-D-吡喃葡萄糖]-7-羟-基3, 8-二甲氧基酮(1-O-[β--Dxylopyranosyl-(1→6)-β-D-glucopyranosyl]-7-hydroxy-3, 8-dimethoxyxanthone, 8)、8-O-[β-D-吡喃木糖(1→6)-D-吡喃葡萄糖]-1, 7-二羟基-3-甲氧基酮(8-O-[β-D-xylopyranosyl-(1→6)-glucopyranosyl]-1, 7-dihydroxy-3-methoxy-xanthone, 9)、1-O-β-D-吡喃葡萄糖-7-羟基-3, 8-二甲氧基酮(1-O-β-D-glucopyranosyl-7-hydroxy-3, 8-dimethoxyxanthone, 10)、异荭草苷(isoorientin, 11)、8-O-β-D-吡喃葡萄糖-1, 3, 5-三羟基酮(8-O-β--Dglucopyranosyl-1, 3, 5-trihydroxanthone, 13)。其余4个还在结构鉴定中。结论所有化合物1~11均为首次从该植物中得到。
[Key word]
[Abstract]
Objective To study the chemical constituents from Swertia kingii.Methods The consti-tuents were isolated and purified by column thromatography methods.Their structures were identified on the basis of physiochemical properties and special analysis.Results Fifteen compounds were obtained from this plant and 11 of them were identified as β-sitosterol(1),methylswertianin(2),gentiacaulein(3),swerchirin(4),8-O-β-D-glucopyranosyl-1,3,7-trihydroxanthone(5),mangiferin(7),1-O-[β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl]-7-hydroxy-3,8-dimethoxy-xanthone(8),8-O-[β-D-xylopy-ranosyl-(1→6)-glucopyranosyl]-1,7-dihydroxy-3-methoxy-xanthone(9),1-O-β-D-glucopyranosyl-7-hydroxy3,8-dimethoxyxanthone(10),isoorientin(11),8-O-β-D-glucopyranosyl-1,3,5-trihydroxanthone(13),Four compounds are being identified.Conclusion All compounds are first found from this plant.
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[基金项目]
青海龙胆科主要药用植物指纹图谱研究(2004-N-142)