[关键词]
[摘要]
目的研究岗梅Ilexasprella根的化学成分。方法采用硅胶、凝胶和RP-HPLC等色谱方法对岗梅根的化学成分进行分离纯化, 并根据理化性质和波谱数据鉴定化合物的结构。结果从岗梅根的70%乙醇提取物中分离得到10个三萜及其皂苷类化合物, 分别鉴定为28-O-β-D-glucopyranosyl pomolic acid(1)、冬青苷XXIX(ilexo-side XXIX, 2)、冬青苷B(ilexoside B, 3)、刺参苷F(monepaloside F, 4)、长圆冬青苷B(oblonganoside B, 5)、3-O-β-D-xylopyranosyl-3β-hydroxyurs-12, 18(19)-dien-28-oic acid 28-β-D-glucopyranosyl ester(6)、毛冬青皂苷B(ilexsapo-nin B, 7)、randialic acid B(8)、毛冬青酸(ilexolic acid, 9)和19-去氢乌索酸(19-dehydroursolic acid, 10)。结论化合物1~9均为首次从该植物中分离得到。
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[Abstract]
Objective To investigate the chemical constituents from the roots of Ilex asprella.Methods The chemical constituents were isolated by silica gel,Sephadex LH-20,as well as RP-HPLC column chromatography.Their structures were identified on the basis of physicochemical properties and spectral analysis.Results Ten triterpenes and triterpenoid saponins were isolated and identified as 28O-β-D-glucopyranosyl pomolic acid(1),ilexoside XXIX(2),ilexoside B(3),monepaloside F(4),oblonganoside B(5),3-O-β-D-xylopyranosyl-3β-hydroxyurs-12,18(19)-dien-28-oic acid 28-β-D-glucopyranosyl ester(6),ilexsaponin B(7),randialic acid B(8),ilexolic acid(9),and 19-dehydroursolic acid(10),respectively.Conclusion Compounds 1-9 are isolated from I.asprella for the first time.
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[基金项目]
广东省自然科学基金团队项目(No.8351063201000003);澳门特别行政区科学技术发展基金(No.013/2008/A1);广东省科技计划国际合作项目(No.2008A050200005)