[关键词]
[摘要]
目的对卫矛Euonymus alatus抗心肌缺血有效部位的化学成分进行研究。方法利用各种色谱法分离化学成分,通过理化性质和波谱法鉴定化合物的结构。结果从卫矛中分离得到5个化合物,分别为1-[3-(α-D-吡喃葡萄糖氧基)-4,5-二羟基苯基]-乙酮(Ⅰ)、8-O-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖基苯乙醇(Ⅱ)、丁香酚苷(Ⅲ)、金丝桃苷(Ⅳ)、橙皮苷(Ⅴ)。结论化合物Ⅰ为新化合物,命名为鬼箭羽苷(guijianyuside),化合物Ⅱ、Ⅲ为首次从卫矛中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of the EtOAc soluble fraction obtained from the stems and branches of Euonymus alatus with anti-myocardial ischemic effect. Methods Chemical constituents were isolated and purified by solvent extraction together with various chromatographic techniques, and the structures were identified by physicochemical properties and spectral analyses. ResultsFive compounds, 1-[3-α-D-glucopyranosyloxy)-4, 5-dihydroxyphenyl]-ethanone (Ⅰ), phenethyl alcohol 8-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (Ⅱ), eugenyl-O-β-D-glucopyranoside (Ⅲ), hyperin (Ⅳ), and hesperidin (Ⅴ) were isolated. Conclusion Compound Ⅰ is determined as a new compound named guijianyuside. Compounds Ⅱ and Ⅲ are isolated from this plant for the first time.
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[基金项目]
“十五”国家科技攻关计划引导项目(2004ba53c)