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[摘要]
目的研究墨旱莲的化学成分。方法应用溶剂法进行提取,硅胶、Sephadex LH-20等手段反复柱色谱分离、纯化,通过熔点、NMR等手段确定结构。结果从其乙醇提取物的石油醚、醋酸乙酯以及正丁醇萃取部分共得到10个化合物,分别为2,2′,5″,2″-三噻吩-5-羧酸(Ⅰ)、β-谷甾醇(Ⅱ)、芹菜素(Ⅲ)、槲皮素(Ⅳ)、木犀草素(Ⅴ)、蟛蜞菊内酯(Ⅵ)、去甲蟛蜞菊内酯(Ⅶ)、旱莲苷C(Ⅷ)、木犀草苷(Ⅸ)、蒙花苷(Ⅹ)。结论化合物Ⅰ为一新天然产物,Ⅹ为首次从墨旱莲中分离得到。
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[Abstract]
Objective To study their chemical components of Eclipta prostrata and identify their chemical structures.Methods The compounds were isolated by chromatography,purified by SephadexLH一20 gel,identified by spectral analyses,and compared with the published data.Results Tencompounds were isolated and identified as 2,27,5”,2”一terthiophene一5一carboxylic acid(I),psitosterol (I),apigenin(I),quercetin(Ⅳ),luteolin(V),wedelolactone(V1),demethyl wedelolactone(Ⅶ),ecliptasaponin C(Ⅷ),luteoloside(Ⅸ),and linarin(X).Conclusion Compound I is a new compoundfrom nature and compound X is obtained from E.prostrata for the first time.
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