目的对芦根中阿魏酸含量和结构进行快速测定和分析.方法溶剂提取,气相色谱-飞行时间质谱测定和分析其含量和结构.结果阿魏酸在芦根提取物中的相对质量分数为5%.根据质谱提供的分子离子和8个特征碎片离子的精确质量和相应的元素组成,提出了阿魏酸分子的裂解途径,结合谱图检索,从而确认该分子的结构.结论气相色谱-飞行时间质谱法测定和鉴定芦根中阿魏酸含量和结构是一种快速、准确、灵敏、可靠的检测方法.

Objective To make a rapid determination of ferulic acid and identification of its structure in rhizome of Phragmites communis(RPC)．Methods The chemical constituents were extracted by solvent and the relative content and structure of ferulic acid in RPC were determined and identified using GC—TOFMS technique．Results By GC—TOFMS。the ferulic acid was successfully isolated from the extracts of RPC in a relative content of 5％．According to the exact masses and corresponding elemental compositions of molecular ion and eight characteristic ions，a possible fragmentation pathway of the ferulic acid molecule was proposed。bv which the molecular structure was confirmed．Conclusion GC—TOFMS technique is a rapid，accurate，sensitive，and reliable method for determination of the relative content of ferulic acid in RPC and identificatiion of its structure．