[关键词]
[摘要]
综合国内外文献,结合笔者开展中药生物转化研究的体会,介绍了国内外中药生物转化的研究现状以及在中药现代化研究中的意义,提出了开展中药全成分转化的思路并分析了进行中药全成分转化研究的可行性及一般方法,并就开展中药全成分转化研究存在的问题和今后需要加强的工作等进行了讨论。认为开展中药全成分生物转化研究对充分发挥中药的潜在价值和我国的中药资源优势开发、形成具有中国特色的生物转化研究体系、开发具有自主知识产权的新药具有重要意义。
[Key word]
[Abstract]
The sign if icance and presen tresearch situation of biotran sformation of Chinese materi-am edica(CMM) were rev iewed in this article.Based on the references and our stud ies in biotran sfor-mationof CMM,the idea of biotran sformation of CMM’stotal constituents was put forward.The fea sibili-ty andgeneral method of biotran sformation of CMM’s total con stituents were ana lyzed,and the ex istingproblem sand the work that should be em pha sized were d iscussed sign if ican tly.biotran sformation ofCMM’s totalcon stituents would be sign if icant to give a full play to CMM’s poten tia l va lue and developmen tof ourcoun try’s dominan tresources,to shape the biotran sformation research system w ith Chinese charac-ter isticsand to develop new drugs of independent in tellectual property.
[中图分类号]
[基金项目]
云南大学理工科校级科研基金资助项目(2002T003SM)