[关键词]
[摘要]
目的 研究生附子AconitumcarmichaeliDebx.强心作用的有效成分。方法 用水提取,色谱分离纯化,通过各种光谱分析鉴定结构。结果 从水溶性部分分得强心作用成分——附子苷,从乙醚提取物中分离鉴定了6种已知的二萜生物碱乌头碱、中乌头碱、尿嘧啶、苯甲酰中乌头原碱、附子灵和次乌头碱。结论 附子苷为一新化合物,具有明显的强心作用。
[Key word]
[Abstract]
Object To isolate and identify the cardiotonic constituents in A conitum carm ichaeli Debx.Methods The active constituents were isolated in water soluble part,purified by chromatographic Methods,and their structureswere identified by physicochem ical properties and spectral data.Results A new component,fuzinoside,was obtained from the aqueous extract and identified as glycerol-2-O-β-D-galactofuranosy 1→3 β-D-galactofuranoside.Six compounds:aconitine,mesaconitine,uracil,benzoylmes aconitine,fuziline,and hypaconitine were obtained Conclusion Fuzinoside is a new cardiotonic component from A.carm ichaelil
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[基金项目]
国家自然基金资助项目(30271583)