目的 研究望春花Magnoliabiondii花蕾的木脂素类化学成分,为制定辛夷的质量标准寻找标准物质,也为了进一步了解其有效成分。方法 硅胶柱色谱分离,波谱分析 (UV、IR、MS、1H NMR、13 C NMR)鉴定结构。结果 分离并鉴定了 4个木脂素 (Ⅰ～Ⅳ )和 1个新木脂素 (Ⅴ )类化合物:veraguensin (Ⅰ )、松脂素二甲醚 (pinoresinoldimethylether,Ⅱ )、木兰脂素 (magnolin,Ⅲ )、里立脂素B二甲醚 (lirioresinol Bdimethylether,Ⅳ )和denudatone(Ⅴ )。结论 化合物Ⅰ和Ⅴ系首次从该植物中分离得到

Object To investigate the chemical constituents i n flower buds of Magnolia biondii in order to seek reference mater ials for making the quality standard of Flos Magnoliae, and also get further knowledge about its effective components. Methods Compounds were isolated by column chromatography with silica gel. Their struc t ures were identified by spectral analysis (IR, MS, 1H-NMR, 1 3C-NMR). Results Four lignams and a neolignan were obta ined and identified. They are veraguensin (Ⅰ), pinoresinol dimethyl ether (Ⅱ), magnolin (Ⅲ), lirioresinol-B dimethyl ether (Ⅳ), and denudatone (Ⅴ). Conclusion Compound Ⅰ and Ⅴ are found in this plant for the first time.

九五”国家科技攻关项目 ( 96 90 3 0 2 0 4)