[关键词]
[摘要]
目的 确认阿魏酸的异构体转换反应及川芎、当归药材中阿魏酸的存在形式。方法 采用高效液相色谱法、液相色谱 -质谱联用等手段研究阿魏酸的异构体转换。结果 反式阿魏酸在常规保存条件下 ,可部分转变成为顺式 ,在川芎和当归药材中 ,反式和顺式阿魏酸是共存的。结论 反式阿魏酸有较好的热稳定性 ,但存在缓慢的异构体转换反应。
[Key word]
[Abstract]
Object To investigate the isomer transition reaction of ferulic acid and the existing form of ferulic acid in Ligusticum chuanxiong Hort. and Angelica sinensis (Oliv.) Diels. Methods HPLC and HPLC-MS were used to confirm the isomer transition of ferulic acid. Results The trans-ferulic acid was translated into cis-ferulic acid partly when its solution was deposited under some routine conditions,and the trans- and cis-ferulic acids could coexist in the Chinese medicinal materials,L. chuanxiong and A. sinensis. Conclusion The trans-ferulic acid is stable thermodynamicly,but could be translated into cis-ferulic acid partly and slowly.
[中图分类号]
[基金项目]
科技部社会公益专项(2001BIB00150)