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[摘要]
目的 比较党参与黄芪提取物对实验性心肌缺血大鼠的保护作用。方法 采用垂体后叶素 (Pit)法建立心肌缺血动物模型,以 导联心电图 T波和 S- T段位移及心率的变化为指标,观察党参和黄芪对实验性心肌缺血大鼠的保护作用。结果 黄芪和党参均可减轻实验性心肌缺血大鼠心电图的 T波抬高,并能减慢心率,但对心电图S- T段的位移无明显作用,并且党参减轻 T波抬高的效果强于黄芪,而减慢心率的作用弱于黄芪。结论 党参和黄芪均对 Pit致实验性心肌缺血起明显保护作用
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[Abstract]
Object To compare the effects of Radix Codonopsis (RC) and Radix Astragali (RA) on ECG of experimental myocardial ischemia rats. methods The model of myocardia ischemia was made by injection of pituitrin (Pit) in rats. The changes of ECG were observed with three parameters, viz. the heart rate, the locomotions of T wave and S T section. Results Both RC and RA can decrease the run up of T wave in ECG of rats with experimental myocardial ischemic injury in which RC is superior to RA. While RA has stronger effect on the slowering of the heart rate than RC.Conclusion Both RC and RA have protective effect on experimental myocardial ischemic injury induced by Pit.
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