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[摘要]
目的选择参附汤方药成分的提取工艺。方法以人参二醇、人参三醇、总生物碱、酯型生物碱、丹参酮 A、原儿茶醛、总糖、干浸膏为指标,在药材粒度、溶剂量、煎提温度、滤过、浓缩等条件相同的前提下,采用半仿生提取 (SBE)法、水提取 (WE)法、半仿生提取醇沉 (SBAE)法、水提醇沉 (WAE)法进行比较研究。结果 8个指标综合评价 Y值为:SBE法 >WE法 >SBAE法 >WAE法。结论参附汤方药成分的提取以 SBE法提取为佳。
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[Abstract]
Object To evaluate the extract technology of SHENFU DECOCTION (SFD) components. Methods Four methods-the semi bionic extraction (SBE), the water extraction (WE), the semi bionic extraction by precipitation with alcohol (SBAE), and the water extraction by precipitation with alcohol (WAE) were used to extract SFD, by taking panaxadiol, panaxitriol, total alkaloid of aconite, aconitine, tanshinone Ⅱ A, protocatechn aldehyde, total sugar and dried extract as the markers and to compare and study the four methods under the same conditions of drug granularity, solvent amount, decocting temperature, filtration, concentration, etc. Results Through the comprehensive evaluation of the eight markers, the comprehensive values Y were SBEWESBAEWAE. Conclusion SBE method is better than the other three methods in the extraction of SFD components.
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