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[摘要]
目的 研究清血降脂胶囊的制备工艺。方法 采用均匀设计方法,以总有机酸、总多糖为指标,对制备胶囊浸膏的提取溶剂比、煎煮时间、醇沉浓度等关键工艺步骤进行考查。结果 该制剂的最佳工艺条件为:药材与溶剂比为1∶10,煎煮2次,每次为60min,醇沉浓度为50%。结论 以本工艺条件提取有效成分,不仅保证有机酸的含量,同时也使多糖不受损失。
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[Abstract]
Object To establish a process for the preparation of QINGXUE JIANGZHI CAPSULE (Hemocathartic Antilipemia Capsule). Methods The study was carried out by uniform experimental design guided by the content of total organic acid and polysaccharide in the resulting preparation, to optimize the ratio of solvents used for the extraction, time needed for the decoction and alcoholic concentration for precipitation. ResultsThe most favorable preparative conditions were: decocting the drug twice with 10 times of water for 60 min each time, and precipitate the product at a concentration of 50% alcohol. Conclusion Products prepared by this process ensured the content of total organic acid with no loss of polysaccharides.
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