目的:测定关木通中总马兜铃酸的含量, 保证临床用药安全有效.方法:紫外分光光度法, 检测波长为310nm.结果:20批关木通样品中总马兜铃酸含量为0.63%～2.84%.结论:各地所用商品关木通中总马兜铃酸含量差异较大, 且与药材性状具一定关系.

To determine the content of total aristolochic acid in the stem of Aristolochia manshuriensis Kom. for the purpose to ensure clinical safety and therapeutic efficacy. 20 samples of the stems of A manshuriensis bought from the market were analyzed by ultraviolet spectrophotometry and detected at a wave length of 310 nm. Their total aris tolochic acid contents varied from 0.63%～2.84%Commercial samples of A manshuriensis used in different localities varied markedly in their total aristolochic acid contents, and seemed to be closely related with the morpho logy of crude drugs.

国家“九·五”攻关项目 No.96-903-02-02