以银杏叶浸膏EGb761为原料,通过预处理、制备色谱和重结晶过程,得到纯度达98%以上的银杏内酯A、B和白果内酯纯品。建立了一种较简单的分离和纯化银杏内酯A、B和白果内酯的方法

A simple method for the isolation and purification of ginkgolide A, B and bilobalide (ginkgo terpene trialctone) was developed A commercially available extract of leaves of Ginkgo biloba L. containing 6% ginkgo terpene trilactone was used as the raw material After partition in EtOAc, the enriched extract was separated to give individual terpenes by preparative liquid chromatography Ginkgolide A, B and bilobalide could be isolated with high purity by recrystallizing in MeOH H 2O

天津市自然科学基金项目!(No.9936 0 6 911)