[关键词]
[摘要]
以瓜蒌、石斛、白芍、川芎、生地、元参、牛膝、五味子、菟丝子、枸杞子、车前子、覆盆子、益母草、泽兰、麦冬、当归组成的中药复方,其水提剂11.27,5.64,2.82g/kg与等量雷公藤多苷组成复方制剂给动物ig.小剂量复方中药+雷公藤多苷组对小鼠急性、慢性炎症及大鼠急性和免疫炎症均有明显的抑制作用,且该作用优于等剂量的雷公藤多苷。中药复方剂量过大可拮抗雷公藤多苷的抗炎作用。
[Key word]
[Abstract]
Water decoction of compositus traditional Chinese medicine, omposed of Fructus rhosanthis, Herba Dendrobii, Radix Paeoniae Alba, etc., at doses of 11. 27. 5. 64, 2. 82 g/kg, mixed the same doses of multi-glycosides of Tripterygium wilfnrdii Hook. f. for oral administration to animal models. 2. 82 g/kg and same dose of mufti-glycosides of T. wilfordii can resist apprently acute and chronic inflammation of mice as well as acute and immunization inflammation of rats, superior to the same dosages of mufti-glycosides of T. wilfordii alone. Too large doses of compositus traditional Chinese medicine can antagonize the antiinflammatory action of mufti-glycosides of T. wilfordii.
[中图分类号]
[基金项目]
大连市科委青年基金