从紫花鄂北贝母 Fritillaria ebeiensis var. purpurea G. D. Yu et P. Li 磷茎非生物碱部分中分离到4种 ent-kaurane骨架的二萜。晶IC₂₀H₃₃OCl,mp153℃～154℃，经波谱分析鉴定其结构为ent-kauran-16β-hydroxy-17-chloride,命名为鄂见新醇(fritillaziebinol).晶 Ⅱ、Ⅲ和 Ⅳ经波谱解析及与标准品对照，分别鉴定为ent-kauran-16β，17-diol,ent-kauran-3β，16β，17-triol,ent-3β-acetoxy-kauran-16β，17-diol,Ⅰ系新的天然含氯二萜， Ⅱ～Ⅳ在该植物中首次得到。

The bulb of Fritillaria ebeiensis var. purpurea G. D. Yu et P. Li is a liliaceous plant grow-ing in the Suizhou district of Hubei province,China. This Plant，easily cultivable in the district，has high al-kaloid content and shows conspicuous antitussive and expectorant effects. The bulbs treated with lime and then bleached in the sun,are called"Ebeibeimu", and are commercially available as a substitute for the prin-cipal Chinese traditional medicine "f3eimu". With regard to the alkaloid constituents of the bulbs, we have al-ready reported the presence of six C-nor-D-homo steroidal alkaloids，but the non basic constituents have not been reported. In our continuing studies on its chemical constituents, a novel ent-kaurane diterpenoid with chloro-substituded C-17 fritillaziebinol(I)was isolated with three known diterpenoids，1，l and N from bulbs of Fritillaria ebeiensis var. purpurea G. D. Yu et P. Li. The compounds 1~N have been identified as the known diterpenoids ent-kauran-16β，17-diol，ent-kauran-3β，16β,17-triol, and ent-3β-acetoxy-kauran-16(β, 17-diol on the basis of spectral data，TLC and mixed mp comparison with authentic samples. CompoundI，C2oH33}C1，mp 153 C一154 C，named fritillaziebinol，is a new ent-kauran diterpenoid with chloro-substi-tuded C-17 has been established as ent-kauran-16卜hydroxy-l7-chloride on the basis of spectral methods in-cluding 2D-NMR techniques