西红花总苷ig能明显延长小鼠的凝血时间，缓解ADP,AA诱导的小鼠肺血栓形成所致的呼吸窘迫症状，明显抑制血小板血栓的形成。家兔体内给药，对ADP和凝血酶诱发的血小板聚集均有明显的抑制作用。

Crocin，the coloring glycoside of Crocus sativus L.，ig prolonged blood coagulation time of mice, and markedly inhibited，dose-dependently, thrombin and ADP-induced blood platelet aggregation of rabbits in vivo. In addition, crocin ig exhibited, in a dose-dependent manner, an inhibitory effect on thrombus formation in rat with arterio-venous shunt and relieved respiratory distress due to pulmonary thrombosis in mice induced by ADP and AA.

五”国家科技攻关项目;国家新药基金