Shenge capsule was found to exhibit an excellent protective effect against arrhythmia caused by aconitineand calcium chloride in rats with deficiency of heart-energy and heart-yin syndrome when given orally(P<-i><0.001 and P<-i><0.05). It also showed obvious protective effect against ventricular fibrillation caused by chloroform in mice. It could increase the arrhythmic threshold value of rabbits caused by electric stimulation.