小鼠自发活动和转轮活动测试结果表明：云芝糖肽能抑制小鼠的自发活动和转轮活动。腹腔注射100mg/kg和200mg/kg云芝糖肽都能显著降低小鼠的自发横向和直向活动以及转轮活动（P＜0.01或P＜0.05），并显示了一定的星效关系。安定2.5/ks的作用明显高于云芝糖肽100ms/kg的作用（P＜0.01），而与其200ms/kg的作用相比，无显著差异（P＞0.05）。

Results of spontaneous and uirrel Wheel activity tests in mice showed that Polysaccharopeptide of Coriolus versicolor could inhibit their spontaneous and squirrel wheel activities. Micegiven intraperitoneal in-jections of PSP（100mg/kg or200mg/kg)showed significant decrease ofnumbers of horizontal and vertical as well as squirrel wheel activities（P<0.05 or P<0. Ol),in a dose-dependent manner. The inhibitory effect of diazepam（2.5mg/kg)was much stronger than that of100mg/kg PSP（P<0.01),but didnot differ signifi-cantle with200mQ/kQ PSP(P<0.05).