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[摘要]
治疗糖尿病中药“玉液汤”中,知母是主药。本文研究了百合科植物知母多糖的降血糖活性。知母根茎经热水提取、乙醇沉淀、稀碱脱蛋白,得到的多糖给小鼠准胃,结果表明知母多糖可使小鼠的血糖及肝糖元含量明显降低,而血脂含量几乎没有变化。若为腹腔给药,该多糖也有降血糖活性。注胃四氧吃陡高血糖小鼠,其血糖含量也有明显下降。
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[Abstract]
Root stem of Anemarrhena asphodeloides was extracted with hot water,treated with ethanol and dilute alkali to temove protein. The polysaccharide thus obtained wasgiven to mice bygastricgavage. Result showed that the polysaccharide can markedly lower the blood sugar and liverglycogen of mice without affecting blood lipid level. Whengiven intraperitoneally,it also showed hypoglycemic activity. For alloxan diabetic mice,the polysaccharide can also markedly lower its blood sugar bygastricgavage.
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