金银花的水溶性部位经大孔树脂柱层析,Rp－18HPLC柱层桥分得4个化合物,经FABMS,IDNMR和2DNMR谱的测定,确定3个三萜皂甙的结构为：3－O－α－L－吡喃鼠李糖基-（1→2）－α－L-吡喃阿拉伯糖基-hederagenin－28－O-β-D-吡喃木糖基-（1→6）-β-D-吡喃葡萄糖酯（I）,3－O－α-L-吡喃阿拉伯糖基-hederagenin－28－O－α－L-吡喃鼠李糖基（1→2）-（β-D-吡喃木糖基-（1→6））-β-D-吡喃葡萄糖酯（Ⅱ）和3－O－α－L-吡喃鼠李糖基-（1→2）-α-L-吡喃阿拉伯糖基-hederagenin－28－O－α－L-吡喃鼠李糖基-（1→2）-（β-D-吡喃木糖基（1→6））-β-D-吡喃葡萄糖酯（Ⅲ）。另-化合物确定为绿原酸四乙酰化物（Ⅳ）。药理实验表明以上化合物对CCl₄。引起的小鼠肝损伤有明显的保护作用。

From the water soluble extract of Flos Lonicera japonica Thunb,three triterpenoid saponins were isofated. On the basis of detailed analysis of ¹HNMR,¹³CNMR,¹H-¹HCOSY,HMBC,HMQC,FAB MS,their structures were decided as 3-O-α-L-arhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin 28-O-β-D-xylpyranosyl(1→6)-β-D-glucopyranosyl ester(I),3-O-α-L-arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl(1→2)[β-D-xylpyranosyl(1→6)}-β-D-glucopyranosyl ester(Ⅱ)and 3-O-α-L-rhamnopyranosyl (1→2)-α-L-arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl(1→2)[β-D-xylpyranosyl(1→6)-β-D-glucopyranosyl ester(Ⅲ),and chlorogenin tetraacetate(Ⅳ).Pharmacological experiment showed that these compounds had cytoprotective effects against carbon tetrachloride induced hepatic injury.