[关键词]
[摘要]
从豆科植物锦鸡儿Caraganasinica的根(中药金雀根)中分得5个异黄酮类成分,分别鉴定为flemichapparninB(Ⅰ),芒柄花素(formononetin,Ⅳ),赝靛黄素(Pseudobaptigenin,Ⅴ),5-羟基-7',4'一二甲氧基异黄酮(Ⅲ))和5-羟基-7-甲氧基-3',4'-二氧亚甲基异黄酮(Ⅱ)。其中化合物Ⅱ为新的天然异黄酮化合物。
[Key word]
[Abstract]
The root of Caragana sinica (Buc' hoz)Rehd' is a Chinese folk medicine which is said to be useful for thetreatment of asthenia syndrome,vascular hypertension, leukorrhagia, arthrodynia, and as antiinflammatory agent. In the course of our search for inhibitors of protein kinase C from Chinese herbs,chemical constituentsof the root of C. sinica was examined. Frorn ethanol extract of this crude drug,five isof1avones were isolatedand identified as flemichapparnin B, formononetin, pseudobaptigenin, 5-hydroxy-7, 4'-dimethoxy isoflavone,and 5-hydroxy-7-methoxy-3', 4' -methylenedioxy isoflavone.
[中图分类号]
[基金项目]
国家自然科学基金