结果表明，给药组小鼠自主活动次数明显减少，脑电图θ波均有不同程度的增加，同时尚有α波的减少。并能增强戊巴比妥钠的中枢抑制作用，使翻正反射发生率明显减少。在小鼠学习能力的实验中，可见小鼠总反应时间、非条件反射潜伏期均被延长，形成条件反射总次数减少。逃避性条件反射顺序号数值加大。表明该药能对小鼠中枢神经系统产生明显的抑制作用。

The effects of Saussurea Flavone Glycoside A1(SFG) on CNS were studied by observing autonomous activity, cortical electric activity, and determing learning ability in mouse.Results showed that mouse autonomous activity decreased obviously (P<0.05) and wave of EEG increased to varying degrees, α wave of EEG decreased in the group of SFG, as compared with the control group (P<0.01). The inhibitory effect of pentobarbital sodium on CNS was enhanced by SFG, the incidence rate of righting refler was remarkably reduced (P<0.01). Besides, in the mouse learning ability experments, the time of mouse total reaction time and the latent period of unconditioned reflex were extended, the total number of iconditioned reflex was reduced and the tactic numbet or avoidable conditioned reflex was ncreased. Therefore, we consider that SFG possesses of sedation, enhances the inhibitory effect of pentobarbital sodium on CNS, reduces mouse learning ability, and extends the accomplishment of learning process and the establishment of consolidatory conditioned reflex.