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[摘要]
以羧甲基纤维素钠作膜材料,研制了中药养阴生肌散的改造剂型─—养阴生肌膜,能用于皮肤磨削手术创面和外伤性创面。动物模型研究表明,该膜防止创面感染,与纱布敷料无明显差异;控制创面组织液渗出及创面快速愈合。此膜明显优于纱布敷料(P<0.01),并有减轻术后水肿和创面刺激作用。该膜原料易得,使用方便,制剂稳定。
[Key word]
[Abstract]
Yangyinshcngji" Film is a modernized wound dressing prepared by incorperating carboxymethyl cellulose into the traditional Chinose powdery prescription for nourishing the "Yiu" and promoting tissue regeneration. When used as dressing in dermabrasivc wound of short-haired albino guinea pigs, in comparison with conventional gauze dressing, it showed no significant differences in preventing wound infection, but is more effective in reducing wound exudation or enhancing wound healing (P0.001 ). It has the extra advantage of reducing cdcma and relieving skin irritation. It is convenient to apply and quality control analysis showed that the film is stable.
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