[关键词]
[摘要]
大豆总甙(TotalSoyasaponinTS)对单纯疱疹病毒Ⅰ型(HSV-I)、柯萨奇Bs(CoxBs)病毒的复制有明显的抑制作用;同时体现出对病毒感染细胞很强的保护作用。其作用机理与TS对病毒的直接杀伤作用有密切关系。临床应用研究表明,对疱疹性口唇炎和口腔溃疡效果显著,有效率达88.8%和76.9%。本研究为应用TS治疗病毒性疾病提供了一定的实验依据。
[Key word]
[Abstract]
Experiment demonstrated that total soyasaponin (TS ) possesed significant inhibitory effect on replication of HSV-1 and CoxB3 viruses and showed marked protective effects on the infected cells (P0.05 and P0.01 ). Preliminary studies on the mechanism of its action showed that TS had a direct killing effect on the viruses. A preparation of TS cream was tried in patients suffering from herpes labialis and oral ulcer. The treatment was highly effective with a cure rate of 88.8% and 76.9% respectively.
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