活血化瘀与扶正补虚组成的柔肝抗纤复方对DMN造模的纤维化大鼠有明显的保肝降酶和抗纤维化作用，其治疗处理优于预防（防治）处理；柔肝抗纤复方对活动性和非活动性肝纤维化的不同作用，显示出活血化瘀药对活动性肝纤维化没有良好的防治作用；DMN造模制作的肝纤维化模型具有较多的优越性，此模型在防治肝纤维化的研究中，有实际意义。

Liver-Softening Anti-Fibrotic Decoction", a preparation consisted mainly of medicinal qerbs with touifying "Qi", flourishing"Yin", activating blood and eliminating stasis, was given by gavage to Dimethyl nitrosamine (DMN) induced fibrotic rat to assess its effect on ative and inactive liver fibrosis. It was found that this preparation, besides its promoting growth aud protein metabolism activeties, can also lower serum alkaline phosphatase, decrease serum hyaluronate and liver hydroxy proline, with a better curative effect on experimental liver fibrosis in rats than its prophylactic effect