3CL-8细胞是小鼠受Friend病毒感染后诱导机体产生的一种永久性红细胞分化反应细胞，致病性极强。应用60％板兰根对小鼠3CL-8细胞进行体内外杀伤，结果表明：在体外细胞培养时，50％板蓝根注射液对3CL-8细胞有强大的直接杀伤作用，最低杀伤浓度可达1∶80。皮下局部注射50％板兰根时有一定的杀伤作用，3CL-8实体瘤有减少趋势。腹腔注射50％板兰根时未见对3CL-8细胞有明显的杀伤作用。

The paper presented here provides evidence of cytotoxicity to mouse 3CL-8 cell of friendcrythrocyte bY 50% Isatis tinctoria injection. In vitro this extract of traditional Chinese medicine exerts a strong cytostatic effect directly on mousc 3 CL-8 cell in tissue culture at a minimum concentration of 1:80 dilution. In vivo, when injected subcutaneously aud locally ontumor site, it showed some cytotoxic effect on 3 CL-8, but showed no significant cytotoxiceffect intrapertoneally.