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[摘要]
研究了氧化苦参碱对人扁桃体淋巴细胞和小鼠脾淋巴细胞在不同丝裂原存在时对增殖能力的影响。结果表明:根据人扁桃体淋巴细胞对PHA,SAC反应能力的不同,氧化苦参碱可使低反应性的人扁桃体淋巴细胞增殖能力提高,而对高反应性的人扁桃体淋巴细胞及正常小鼠脾细胞增殖则表现为抑制作用。提示氧化苦参碱对淋巴细胞增殖的影响和细胞状态密切相关。
[Key word]
[Abstract]
Oxymatriue is $a alkaloid from Traditional Chlnesa Medicine, Sop6ora jlavescens Ait. which has many pharmacological effects. We stu,iied tho affects of oxymatrine on the proliferation of human tonsillar cells and mouse splenocytes with or without mitogens. The results show that,. oxymatrine can augment the proliferation of the human tonsillar cells which show low PHA& tSAC resp,use capacity. Qa the other hand, oxymatrina can inhibit the proliferation of the human tonsillar cells which show high PHA&SAC responses capacity. The effects of oxymatine on muse spleuocYtes are the same with the latter.
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