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[摘要]
检测了油酸型呼吸窘迫综合征大鼠血气和酸碱指标的变化,并观察了红芪对其影响。结果表明,红芪有提高油酸型呼吸窘迫综合征大鼠PaO2、O2Sat,降低PaCO2的作用,并能纠正大鼠酸碱的内稳失常,从而对红芪治疗呼吸窘迫综合征提供了理论依据。
[Key word]
[Abstract]
Yuzhizi is the seed of Akebia quinata (Thunb. ), A.trifoliota (Thunb.) Koidz.and A.trifoliata(Thunb.) Koidz.var.australis(Diels) Rehd.Two triterpenoid saponins of hederagenin 3-O-glycosides have been isolated from the seeds of A. trijoliata (Thunb.) Koidz.var.australis (Diels) Rehd. for the first time. They were idcntified by spectroscopic(EI-MS, FABMS, 1H, 13CNMR and 2 DNMR) and chemical methods (acid/base hydrolysis) as Ⅰ:3-O-β-D-xylo-pyranosyl-(1-2)-α-L-arabinopyranoside hederagenin (saponin B); Ⅱ: hederagenin 3-O-β-D-glucopyranosyl-(1-2)-α-L-arabinopyranoside (saponin C).
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