中药通过独特的药理作用影响机体的能量代谢过程，在安全性评价中发挥着关键作用。中药能纠正能量代谢失衡，在临床实践中具有重要的治疗价值，然而，其不良反应会导致能量代谢紊乱。聚焦于能量代谢在中药安全性评价中的研究进展，深入探讨外源性、内源性因素如何影响能量代谢，旨在为中药安全性评估与能量代谢的关联提供科学依据。

Traditional Chinese medicine (TCM) influences the body's energy metabolism process through its unique pharmacological actions, which plays a key role in safety evaluation. TCM can correct the imbalance of energy metabolism and has important therapeutic value in clinical practice. However, its adverse reactions may lead to energy metabolism disorders. This article focuses on the research progress of energy metabolism in the safety evaluation of TCM, deeply explores how exogenous and endogenous factors affect energy metabolism, and aims to provide a scientific basis for the association between TCM safety assessment and energy metabolism.

R28

国家自然科学基金项目（82004093）;国家自然科学基金项目（81873194）;国家自然科学基金项目（82204938）;河南省医学科技攻关计划联合共建项目（LHGJ20240427）