三七 Notoginseng Radix et Rhizoma 是药食两用的名贵中药之一，其使用历史悠久，疗效显著。但市场上的三七质量参差不齐，甚至存在以次充好和掺伪、掺杂等现象。此外，三七的外源性农药、重金属与有害元素等的污染也不容忽视。从有效性和安全性 2 个方面入手，对基于有效成分的三七真伪鉴别和内在质量评价及外源性有毒有害污染物检测等研究现状进行综述，为更科学、合理的三七整体质量评价提供参考，为保障三七的药用价值和控制食药用安全性风险奠定基础。

Sanqi (Notoginseng Radix et Rhizoma) is one of the valuable traditional Chinese medicines with dual purposes as both food and medicine. It has a long history of use and remarkable therapeutic effects. However, the quality of Notoginseng Radix et Rhizoma varies in markets. There are even illegal behaviors such as substitution, adulteration, and mixing with inferior materials. In addition, the pollution of exogenous pesticide residues, heavy metals and harmful elements in Notoginseng Radix et Rhizoma cannot be ignored. From the perspectives of effectiveness and safety, this article reviews research progress on authenticity identification based on active ingredients and intrinsic quality evaluation of Notoginseng Radix et Rhizoma, as well as detection and determination of exogenous toxic and harmful pollutants in Notoginseng Radix et Rhizoma. It would provide a reference for a more scientific and reasonable holistic quality evaluation of Notoginseng Radix et Rhizoma, and lay a foundation for ensuring its medicinal value and controlling the safety risk for food and medicine use.

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国家自然科学基金资助项目(82104390);国家药品监督管理局中药质量控制重点实验室开放研究课题(2023-ZY-01);上海市中药和保健食品品质与安全检测专业技术服务平台(21DZ2290200)