目的 分析“一带一路”视域下药食两用本草桑叶的研究现状及热点，为进一步开发利用中药材提供思路。方法 以国内权威数据库中国知网（CNKI）、维普（VIP）、万方（Wanfang）和国外权威数据库 Web of Science（WOS）为文献来源，借助 COOC 和 VOSviewer 软件对我国“一带一路”区域省市及“一带一路”沿线国家在 2013 年 1 月—2024 年 9 月发表的桑叶相关科学研究进行检索和分析，并绘制知识图谱。结果 共检索到桑叶中文相关科学研究文献 520 篇，涉及我国“一带一路” 18个省市， 以及桑叶英文相关科学研究文献 219 篇，涉及中国和 17 个“一带一路”沿线国家。其中，中文研究数量整体呈下降趋势，而英文呈逐步增长趋势。研究区域上，“丝绸之路经济带”（一带）以新疆、重庆为代表，“21 世纪海上丝绸之路”（一路）以广东、浙江为代表；“一带一路”沿线国家以巴基斯坦、马来西亚为代表。主要收录期刊有《实用中医内科杂志》《食品科学》、Molecules、 Journal of Ethnopharmacology；涉及学科方向主要为中药学、中医学、食品科学。研究热点上，我国“一带”区域13 个省市主要围绕桑叶活性成分提取、检测、药理作用及药用桑叶进行研究，“一路”区域 5 个省市注重于桑叶临床研究、数据挖掘、配伍规律及桑叶茶的研究；国际上我国及“一带一路”沿线国家研究热点为桑叶黄酮和 1-脱氧野尻霉素、治疗糖尿病机制、网络药理学、肠道菌群。结论 “一带一路”视域下桑叶研究主要集中于有效成分提取、 含量测定、药理作用、临床研究、数据挖掘、配伍规律、桑叶茶和治疗糖尿病机制等，在医药和食品方面有潜在价值。

Objective To analyze the research status and hot spots of medicinal and edible herbal Sangye (Mori Folium) from perspective of the Belt and Road, providing new ideas for further development and utilization of traditional Chinese medicine. Methods Using domestic and foreign authoritative databases CNKI, VIP, Wanfang, and Web of Science (WOS) as literature sources, COOC and VOSviewer software were used to retrieve and analyze scientific research of medicinal and edible herbal Mori Folium included from January 2013 to September 2024 in districts of the Belt and Road and countries along the Belt and Road, then visualization knowledge maps were drawn. Results A total of 520 Chinese literature of 18 districts of the Belt and Road and 219 English literature of China and 17 countries along the Belt and Road related to the scientific research of medicinal and edible herbal Mori Folium were retrieved. The number of domestic literature showed a gradual downward trend, while the number of foreign literature was gradually increasing. The main study area was Xinjiang and Chongqing of the Silk Road Economic Belt (short for Belt), Guangdong and Zhejiang of the 21st Century Maritime Silk Road (short for Road), and the countries along the Belt and Road were represented by Pakistan and Malaysia. Research journals were mainly involved in Journal of Practical Traditional Chinese Internal Medicine, Food Science, Molecules, and Journal of Ethnopharmacology. Traditional Chinese pharmacology, traditional Chinese medicine and food science were key research directions. In the respect of research hot spots, the 13 districts in the Belt focus on Mori Folium extraction of effective ingredients, detection, pharmacological effects and medicinal Mori Folium, while the five districts in the Road focus on clinical research, data mining, compatibility rules and Mori Folium tea. The international research hot spots in China and countries along the “the Belt and Road” are Mori Folium flavonoids and 1-deoxynojirimycin, the mechanism of treatment in diabetes mellitus, network pharmacology, and gut mircrobiota. Conclusion The research of Mori Folium mainly focus on the ingredients extraction, determination, pharmacological effects, clinical research, data mining, compatibility rules, Mori Folium tea and the mechanism of treatment in diabetes mellitus in the Belt and Road perspective, which have potential value in pharmaceutical and food field.

R282.71;G350

北京中医药大学"双一流"重点学科建设项目(040201011009);国家自然科学基金项目(82274587);石河子大学自主科研项目(ZZZC2023024);石河子大学高层次人才科研启动项目(RCZK202448)。