甘草Glycyrrhizae RadixetRhizoma药材是我国常用的中药，甘草黄酮是从甘草中提取出来的一类小分子植物黄酮类化学成分，根据其结构的不同，可将甘草黄酮分为黄酮、二氢黄酮、黄酮醇、异黄酮和查耳酮。甘草黄酮具有抗氧化、抗炎、抗肿瘤等生物活性，近年来，许多研究发现其对于调节糖脂代谢的作用显著，具有较好的开发前景，但目前尚缺少针对甘草黄酮调节糖脂代谢作用及其机制的总结归纳。对甘草黄酮类化合物对糖脂代谢的影响以及作用机制进行综述，旨在为糖脂代谢紊乱相关疾病的中医防治提供参考。

Glycyrrhizae RadixetRhizoma(Licorice) flavonoids are plant-derived chemicals of small molecule extracted from licorice, a traditional Chinese herbal medicine commonly used in China. According to their structure, licorice flavonoids can be divided into flavones, flavanones, flavonols, isoflavones and chalcones, which have been shown to have varieties of biological activities such as anti-oxidant, anti-inflammatory and anti-tumor. In recent years, many studies have found their important roles in regulate glucose and lipid metabolism, thereby showing a potential value for further development. However, there is no summary of the mechanism of licorice flavones regulating glucose and lipid metabolism. This paper reviews the effects of licorice flavonoids on modulating glucose and lipid metabolism and the underlying mechanisms of their actions, aiming to provide reference for prevention and treatment of chronic diseases related to disorders of glucose and lipid metabolism with traditional Chinese medicine.

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国家自然科学基金资助项目（82204043）;湖南省卫生健康委项目（202112021806）;中南大学研究生自主创新项目（1053320232412）