天麻Gastrodia elata具有息风止痉、平抑肝阳、祛风通络的功效，含有天麻素、天麻苷元、天麻多糖等主要成分。总结了天麻中的主要酚类成分，阐明了天麻素、对羟基苯甲醇、巴利森苷、香草醛等酚类成分对心脑血管疾病如缺血性脑损伤、血管性痴呆、缺血性心肌损伤、高血压、动脉粥样硬化、血凝血栓、炎症等的药理作用，探讨了天麻酚类成分通过抗氧化、调节功能性蛋白表达、抗凋亡、抗炎等机制治疗心脑血管疾病的作用机制，为天麻酚类成分的深入研究提供参考和依据。

Gastrodia elata has the effects of calming endogenous wind and relieving spasm, suppressing hyperactive liver and subsiding yang, expelling wind and dredging collaterals, and contains main components such as gastrodin, p-hydroxybenzyl alcohol and gastrodia polysaccharide. Main phenolic components in G. elata were summarized, and pharmacological effects of gastrodin, p-hydroxybenzyl alcohol, parishin, vanillin and other phenols on cardio-cerebralvascular diseases such as ischemic brain injury, vascular dementia, ischemic myocardial injury, hypertension, atherosclerosis, blood coagulation thrombosis and inflammation were clarified in this paper. Mechanism of G. elata phenolic components in treatment of cardio cerebral vascular diseases through antioxidant, regulating functional protein expression, anti-apoptosis, and other mechanisms was explored, in order to provide a reference and basis for in-depth study of phenolic components in G. elata.

国家高端外国专家项目(GDT20186100426);陕西省重点研发项目(2020NY-139);陕西省创新能力支撑计划项目(2019XY-04)