[关键词]
[摘要]
组分中药是以中医药理论为指导,遵循方剂配伍理论与原则,吸收现代药物研制方法和技术,由有效组分配伍而成的现代中药,是创新中药研究的一种途径。作为中药现代化的重要成果,组分中药较传统中药来说具有更清楚的物质基础和作用机制,有效性也得到了广泛的研究与认可。且组分中药更符合现代药物安全、有效、稳定、可控的特征。组分中药的稳定性因其化学构成的特殊性而具有不同的特点及研究方法。对组分中药的来源、稳定性影响因素、研究现状及其提高稳定性的方法等进行综述,旨在从稳定性角度为组分中药的研发提供科学依据。
[Key word]
[Abstract]
Component-based Chinese medicine (CCM), following the compatibility theory and principle of prescription, adopting modern drug R&D and technologies, made up of the compatibility of active components, is considered as an innovative research methodology for traditional Chinese medicine (TCM) modernization. As an important achievement in the modernization of TCM, compared with TCM, CCM has a clearer material basis and action mechanism than TCM, and its effectiveness has also been widely studied and recognized. And CCM is more consistent with the characteristics of modern medicine that are safe, effective, stable and controllable. The stability of CCM has different characteristics and research methods because of its special chemical composition. A review of the source, influencing factors of stability, status, and methods to enhance the stability of CCM is aimed to provide scientific basis for further development of CCM.
[中图分类号]
[基金项目]
国家自然科学基金面上项目(82074280);国家自然科学基金面上项目(81873191)