[关键词]
[摘要]
目的 研究紫藤属植物紫藤Wisteria sinensis茎的化学成分。方法 利用硅胶柱色谱、聚酰胺柱色谱、Sephadex LH-20凝胶柱色谱法及半制备高效液相色谱等方法分离纯化,并结合理化性质和现代波谱技术鉴定化合物结构。结果 从紫藤茎甲醇提取物中分离得到14个异黄酮类化合物,分别鉴定为鸢尾黄素-7-O-β-D-(6″-O-乙酰基)-葡萄糖苷(1)、7,3',4'-三羟基异黄酮(2)、芒柄花黄素(3)、阿佛洛莫生(4)、樱黄素(5)、鹰嘴豆芽素A(6)、7,3',5'-三羟基-4'-甲氧基异黄酮(7)、8-甲雷杜辛(8)、鸢尾苷(9)、染料木苷(10)、降紫香苷(11)、芒柄花苷(12)、葛花宁(13)、苦参醇O(14)。结论 化合物1是新化合物,命名为鸢尾苷A;化合物2、5、7、9~11、13、14为首次从紫藤属植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents from the stems of Wisteria sinensis. Methods The 14 chemical constituents were isolated and purified by silica gel, polyamide, Sephadex LH-20 column chromatography, and semi-preparative HPLC, and their chemical structures were identified by physico-chemical constants and spectral data. Results Fourteen isoflavones were isolated from the methanol extract of the stems of W. sinensis and identified as tectorigenin-7-O-β-D-(6″-O-acetyl)-glucoside (1), 7,3',4'-trihydroxyisoflavanone (2), formononetin (3), afromosin (4), prunetin (5), biochanin A (6), gliricidin (7), 8-O-methylreyusin (8), tectoridin (9), genistin (10), sissotrin (11), ononin (12), kakkanin (13), and kushenol O (14). Conclusion Compound 1 is a new compound named as tectoridin A, and compounds 2, 5, 7, 9-11, 13, and 14 are obtained from the genus Wisteria for the first time.
[中图分类号]
R284.1
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