金叶败毒颗粒是同济医院原研的临床常用中药制剂，临床主要用于治疗温热病（急性感染性疾病），尤其是病毒性肺炎等上焦热毒证。在此次新型冠状病毒肺炎（COVID-19）疫情中，金叶败毒颗粒取得了一定的预防与治疗效果，被多省列入COVID-19防控药品。综述金叶败毒颗粒的处方来源、药理作用和临床研究现状，并讨论该复方制剂防治COVID-19的可能机制，为其后续临床和基础研究提供研究思路与研究线索。

Jinye Baidu Granules is a commonly used Chinese materia medica preparation originated from Tongji Hospital, which is mainly adopted for treatment of warm heat diseases (acute infectious diseases), especially viral pneumonia and other heat-toxin in upper energizer. In this epidemic situation of COVID-19, Jinye Baidu Granules has achieved certain prevention and treatment effect, and is included in prevention and control drugs of COVID-19 in many provinces. In this paper, the prescription source, pharmacological action and clinical research status of Jinye Baidu Granules were reviewed. At last, the possible mechanism of the compound preparation in the prevention and treatment of COVID-19 was discussed, which provides ideas and clues for the follow-up clinical and basic research.

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