多环多异戊烯基间苯三酚衍生物（polycyclic polyprenylated acylphoroglucinols，PPAPs）为藤黄科植物的主要活性成分，其结构新颖，且具有抗菌、抗病毒、抗肿瘤、抗抑郁等多种生物活性，是目前天然产物研究的热点之一。对近年来从植物中分离得到的226个天然多环多异戊烯基间苯三酚衍生物化学结构、生物活性等方面的研究概况进行综述，以期为该类化合物的进一步研究提供参考。

As major active components of the plant of Guttiferae family, polycyclic polyprenylated acylphoroglucinols (PPAPs) have become a hot topic in natural product studies for their novel structures and varied bioactivities such as antibacterial, antiviral, antitumor, and antidepressant activities. In this paper, the chemical structures and bioactivities of 226 natural PPAPs have been summarized. It may provide the reference for the further studies of PPAPs.

国家自然科学基金资助项目（21502057）