生物碱是大多数乌头属药用植物的主要有效成分，具有较高的药理活性和药用价值，但也是其主要的毒性成分，为便于对乌头属植物水解产物的深入研究，主要从中药模拟炮制现状、乌头属植物所含的生物碱种类、水解机制研究现状及液质联用方法几个方面进行综述。

Alkaloids are the main active ingredients of most plants in Aconitum L., with high pharmacological activity and medicinal value. But it is also the main toxic components. As for the in-depth study on hydrolysate of plants in Aconitum L., this paper mainly summarized the current situation of Chinese medicine simulation processing, Aconitum alkaloids containing plant species, hydrolysis mechanism, and research status by LC-MS method.

国家自然科学基金资助项目“基于中药模拟炮制和细胞膜色谱法的新疆准噶尔乌头生物碱水解机制及产物毒效活性研究”（81460603）