作为控释制剂的典型代表,渗透泵制剂近年来已经成为中药新剂型研究的一个热点。通过查阅有关文献资料,从渗透泵制剂的结构类型、中药渗透泵制剂的辅料、中药渗透泵制剂的处方与制备、体内评价方法、目前存在的问题几个方面对近几年中药渗透泵制剂的研究进展进行了综述,旨在为开发中药渗透泵制剂提供思路和方法。

As a representative of controlled release preparations, osmotic pump has become a hot spot in the new preparation researches of Chinese materia medica (CMM). This paper reviewed CMM osmotic pump preparation from the following aspects:structure type of osmotic pump preparation, adjuncts of osmotic pump preparation of CMM, in vivo evaluation, and problems existing currently, which aimed to provide ideas and methods for the development of CMM osmotic pump preparation.

国家自然科学基金面上项目(81473549);国家科技重大新药创制专项(2014ZX09304-306-04);教育部中央高校教师基本科研专项(XDJK2009C084)