中药现代化核心之一是方剂配伍规律的分析,而"宏观配伍"规律及"微观配伍"规律的研究则是其2个重要组成部分。目前,由于"宏观配伍"规律研究存在的不足,使其研究思路过于狭窄,严重制约了中药现代化的发展。在中医药理论指导下,从中药研究的现状及不足、辨证论治、灰色理论、多元统计方法的应用、可行性分析及前景5个方面,进一步系统深入地阐述以"灰色筛选法"为基础的中药研究新模式,以期为中药现代化的发展提供新的思路。

The compatibility law analysis of traditional Chinese medicine(TCM) is the core of modernization of TCM. Furthermore, "macro compatibility" and "micro compatibility" are two important components of formula compatibility. At present, due to the lack of research on the law of "macro compatibility", the research ideas are too narrow, which seriously restricts the development of modernization of Chinese materia medica(CMM). Under the guidance of TCM theory, we explore the study on the new mode of "grey screening" whose components are divided into the functional units by the current situation and deficiency of CMM research, treatment based on syndrome differentiation, grey systematology, the action of multivariate statistical methods, and new idea on the feasibility study and application prospect as well.

江西省研究生创新专项资金项目(YC2015-S356);天津中医药大学中西医结合学院研究生教育校外创新实践基地科技创新基金(ZXYCX201510)