红芪主要含有糖类、黄酮类及苯丙素类等化学成分,在抗肿瘤方面有着广阔的应用前景。近年来对红芪的抗肿瘤作用研究较多,主要通过抑制肿瘤细胞的生长、诱导肿瘤细胞凋亡、上调机体免疫功能以及协同化疗药物等发挥抗肿瘤作用,其主要活性成分为红芪多糖,黄酮和皂苷也具有一定的抗肿瘤作用。综述了红芪的化学成分及抗肿瘤作用机制的研究进展,为其进一步开发利用提供理论依据。

Hedysari Radix (HR) mainly consists of chemical constituents such as sacchcrides, flavonoids, phenylpropanoids, etc. HR has broad application prospects in antitumor effect. In recent years, the researches on the antitumor function of HR are frequently reported, and the main active ingredients in HR are polysaccharides, flavonoids, and saponins. The active ingredients of HR mainly inhibit the growth of tumor cells, induce the apoptosis of tumor cells, enhance the immune system, and cooperate with chemotherapy drug to exert the antitumor effect. This paper reviews the advances of the chemical constituents and antitumor effects of HR, providing theoretical basis for its further development and utilization.