目的 研究圆苞金足草Goldfussia pentstemonoides全草的化学成分。方法 采用色谱技术进行分离纯化,根据波谱数据并参考文献鉴定化合物结构。结果 从圆苞金足草95%乙醇提取物的正丁醇萃取部位分离得到10个芳香类化合物,分别鉴定为毛柳苷(1)、3,4,5-三甲氧基苯酚-1-O-6-L-鼠李糖基-(1→6)-O-β-D-葡萄糖苷(2)、异类叶升麻苷(3)、isonuomioside A(4)、苯甲醇-O-β-D-吡喃葡萄糖苷(5)、淫羊藿次苷F2(6)、(-)-lyoniresinol 3α-O-β-D-glucopyranoside(7)、(+)-异落叶松脂素-9-O-β-D-吡喃葡萄糖苷(8)、脱咖啡酰基毛蕊糖苷(9)、dehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside(10)。结论 所有化合物为首次从圆苞金足草中分离得到。

Objective To study the chemical constituents from the whole plant of Goldfussia pentstemonoides. Methods The compounds were separated and purified by chromatographic methods. The structures were identified by spectroscopic analyses. Results Ten compounds were isolated from the n-butanol fraction of 95% ethanol extract in the whole plants of G. pentstemonoides and identified as salidroside (1), 1-(α-L-rhamnosyl-(1→6)-O-β-D-glucopyranosyloxy)-3,4,5-trimethoxybenzene (2), isoacteoside (3), isonuomioside A (4), benzyl-O-β-D-glucopyranoside (5), lcariside F2 (6), (-)-lyoniresinol 3α-O-β-D-glucopyranoside (7), (+)-isolariciresinol-9-O-β-D-glucopyranoside (8), decaffeoylverbascoside (9), and dehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside (10). Conclusion All compounds are isolated from G. pentstemonoides for the first time.

江西省卫生厅项目(2014A005);江西民族传统药现代科技与产业发展协同创新中心子课题(JXXT201402017)