目的 研究芳香新塔花Ziziphora clinopodioides的化学成分。方法 采用色谱分离技术进行分离和纯化,并通过核磁共振谱鉴定化合物的结构。结果 从芳香新塔花的乙醇提取物中分离得到21个化合物,分别鉴定为原儿茶酸(1)、云杉素(2)、迷迭香酸(3)、咖啡酸(4)、木犀草素(5)、金雀异黄酮(6)、irisdichotototin D(7)、乔松素-7-O-芸香糖苷(8)、金合欢素-7-O-芸香糖苷(9)、4-羟基-3-甲氧基苯乙酮-4-O-β-D-芹糖-(1→6)-β-D-吡喃葡萄糖苷(10)、黄芩素(11)、山柰素(12)、白杨素-7-O-芸香糖苷(13)、槲皮素(14)、芹菜素(15)、polybotrin(16)、1-O-对羟基肉桂酰单甘油酯(17)、5-羟甲基-2-呋喃甲醛(18)、金合欢素(19)、6,8-二-C-β-D-葡萄糖白杨素(20)、邻苯二甲酸二丁酯(21)。结论 化合物5～8、10～12、16～18、20～21为首次从该植物中分离得到。

Objective To investigate the chemical constituents of the Ziziphora clinopodioides. Methods The compounds were isolated and purified by means of various chromatographic techniques and their structures were identified on the basis of NMR spectral data. Results Twenty-one known compounds were isolated from the ethanol extract of the dry stems of P. amarus and their structures were identified as protocatechuic acid (1), picein (2), rosmarinic acid (3), cafferic acid (4), luteolin (5), 4',5,7-trihydroxy isoflavone (6), irisdichotototin D (7), pinocembrin-7-O-rutinoside (8), acacetin-7-O-rutinoside (9), 4-hydroxy-3-methoxy-acetophenone-4-O-β-D-apiofuranosy-(1→6)-β-D-glucopyranoside (10), baicalein (11), kaempferide (12), chrysin-7-O-rutinoside (13), quercetin (14), apigenin (15), ploybotrin (16), 1-O-p-coumaroylglycerol (17), 5-(hydroxymethyl)-2-furancarboxaldehyde (18), acacetin (19), 6,8-di-C-β-D-glucosylchrysin (20), and dibutyl phthalate (21). Conclusion Compounds 5—8, 10—12, 16—18, and 20—21 are first obtained from this plant for the first time.

国家自然科学基金资助项目(21365018);新疆生产建设兵团科技攻关项目(2011AB030)